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目的全面掌握霍乱流行区江河段霍乱弧菌污染的状况并评价消除污染的措施及其效果。方法于1998年5月4日~7月1日对流行区A、B、C河流按每隔300~500米设立取水点 ,每2~3天采样1次 ;1998年7月~2001年12月对13个曾反复阳性点按月进行霍乱弧菌监测。采取对下水道污水消毒,拆除沿江两岸厕所和人群查源等措施以消除污染。结果1998年4月28日~6月1日在流行区29个取水点检出霍乱弧菌。毒力测定人源株以中等毒力为主 (68.8% ),而水源株以弱毒为主 (66.7% )。1998年7月至2001年12月采水796份 ,均未检出霍乱弧菌 ,24份水样L型菌、非可培养状态也为阴性。结论该流行区江河段遭受一时性霍乱弧菌污染 ,1998年6月2日以后已彻底消除 ,未发生水型传播疫情 ,1998年8月~2001年12月 ,该区域也未再有霍乱病例发生 ,表明消除措施效果显著 ,也证明当地霍乱疫情系输入性
Objective To comprehensively grasp the status of Vibrio cholerae contamination in the rivers of cholera epidemic area and evaluate the measures to eliminate it and its effects. Methods From May 4 to July 1, 1998, water points were set up every 300 ~ 500 meters for the A, B and C rivers in the endemic areas and once every 2 ~ 3 days. From July 1998 to December 2001 Months 13 were repeatedly positive point by month Vibrio cholerae surveillance. Sewage disinfection to take sewers, demolition of toilets along the river and people source and other measures to eliminate pollution. Results From April 28 to June 1, 1998, V. cholerae was detected at 29 water intake sites in the endemic areas. The virulent strains were mainly moderately virulent (68.8%), while the water strains were mainly virulent (66.7%). From July 1998 to December 2001, 796 water samples were collected, no V. cholerae and 24 L-like bacteria were detected, and the non-culturable state was also negative. Conclusions The river section of the epidemic area was polluted by V. cholerae once and for all. It was completely eliminated after June 2, 1998, and no waterborne transmission epidemic occurred. From August 1998 to December 2001, no cases of cholera were found in this area Occurred, indicating that the elimination of the effect of significant results, but also to prove that the local cholera epidemic input