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对425例病毒性肝炎患者及160例献血员进行血清抗-HCV 测定,结果在献血员、急性非甲非乙型肝炎、HBsAg 阴性的慢性肝炎肝硬化及 HBsAg 阴性的亚急性重症肝炎患者中,阳性率分别为1.87%(3/160)、12.8%(5/39)、53%(9/17)和40%(2/5)。另有19例与 HBV重叠感染,其发生率分别为:急性乙肝1.6%(2/118)、慢性乙肝7.7%(11/142)、亚急性重症乙肝13.8%(8/58)。说明无论单独感染或与 HBV 重叠感染,HCV 在肝炎的慢性化和重症化中的作用都不可忽视。献血员中将近2%的 HCV 感染率亦提示我们应该严格筛选献血员和把握输血指征。
Serum anti-HCV was measured in 425 patients with viral hepatitis and 160 blood donors. Among the blood donors, acute non-A non-B hepatitis, HBsAg negative chronic liver cirrhosis and HBsAg negative subacute severe hepatitis, The positive rates were 1.87% (3/160), 12.8% (5/39), 53% (9/17) and 40% (2/5), respectively. Another 19 patients were infected with HBV, the incidence rates were 1.6% (2/118) for acute hepatitis B, 7.7% (11/142) for chronic hepatitis B and 13.8% (8/58) for subacute severe hepatitis B, respectively. It shows that the role of HCV in chronic hepatitis and chronic severe hepatitis can not be neglected either alone or in combination with HBV infection. Nearly 2% of the blood donors’ HCV infection rates also suggest that we should strictly screen blood donors and take blood transfusion indications.