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对奥得福尔制剂的药效学定量杀菌试验、抗病毒试验及临床应用的结果表明 :奥得福尔制剂原液 ,1∶ 1稀释液及 1∶ 5稀释液对大肠杆菌、金黄色葡萄球菌和白色念珠菌作用 10 min,杀灭率均可达 99.9%以上 ;消毒液放置室温下稳定 ,有机物的存在对杀灭作用有轻度影响 ,但杀灭率仍可达 99.9%以上 ;体外抗病毒试验结果表明 ,该制剂的主要抗病毒功效成分——黄精多糖 ,对单纯疱疹病毒的空斑抑制率达到 10 0 % ;稳定性试验表明 ,该制剂常温下存放一年其杀菌率不变 ;动物急性毒性试验表明 ,本品属实际无毒级 ;对正常皮肤无刺激性 ;家兔眼刺激试验表明 ,对眼粘膜无刺激性。经临床 60例应用观察 ,对生殖器疱疹 ( GH)安全有效 ,显效率为 86.7% ,总有效率为 97.8% ;对细菌性和真菌性阴道炎治愈率分别为 85.7% ,78.6% ;显效率为 10 0 % ,92 .9% ,总有效率为 10 0 % ,97.8%。
Quantitative bactericidal test, anti-virus test and clinical application of OderForest’s formulations showed that OderForm’s stock solution, 1: 1 dilution and 1: 5 dilution on Escherichia coli, Staphylococcus aureus And Candida albicans for 10 min, the killing rates were all over 99.9%. The disinfectant solution was stable at room temperature and the presence of organic compounds had a slight effect on the killing effect, but the killing rate was still above 99.9% The results of the virus test showed that the main anti-virus active ingredient of the preparation, Polygonatum Polysaccharide, had a plaque inhibition rate of 100% against the herpes simplex virus; the stability test showed that the bactericidal rate of the preparation was kept unchanged at room temperature for one year; Animal acute toxicity test showed that this product is actually non-toxic grade; non-irritating to normal skin; eye irritation test in rabbits shows no irritation to eye mucosa. Clinical application of 60 cases of observation, the genital herpes (GH) safe and effective, markedly effective rate was 86.7%, the total effective rate was 97.8%; for bacterial and fungal vaginitis cure rates were 85.7%, 78.6%; significant efficiency was 10 0%, 92 .9%, the total effective rate was 10 0%, 97.8%.