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作者应用双盲法比较克霉唑与发癣退对皮肤癣菌病及克霉唑与制霉菌素对表浅串珠菌感染的疗效,特别注意停药一月后的复发情况。所有病人均经显微镜检查和培养证实。对皮肤癣菌病人随意使用1％克霉唑霜或1％发癣退霜;对表浅串珠菌感染随意使用1％克霉唑霜或制霉菌素霜(每克含制霉菌素10万单位)。每日早晚各搽一次,共4周。于治前、两周后,4周后及8周后(即停药4周后)分别作病情评价,评价之前停搽药24小时。
The authors used double-blind method to compare the efficacy of clotrimazole and ringworm on dermatophytosis and clotrimazole and nystatin against streptococcus infection, with special attention to the recurrence after one month withdrawal. All patients were confirmed by microscopy and culture. For patients with dermatophytes, 1% clotrimazole cream or 1% fulguration is allowed to be used at will; 1% clotrimazole cream or nystatin cream (per gram nystatin 100 000 units) ). Apply once daily morning and evening for 4 weeks. Before treatment, two weeks later, four weeks later and eight weeks later (that is, after stopping for 4 weeks), respectively, for evaluation of disease, drug evaluation stopped smoking before 24 hours.