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目的观察更昔洛韦联合泛昔洛韦治疗带状疱疹的临床疗效。方法选取患者62例作为研究对象,随机分为观察组和对照组,每组31例。观察组采用更昔洛韦注射液联合泛昔洛韦胶囊治疗;对照组采用泛昔洛韦胶囊治疗。均同时服用维生素B1,局部外用炉甘石洗剂和阿昔洛韦乳膏。疗程均为7 d。观察比较2组临床疗效,止疱时间、止痛时间及结痂时间。结果观察组总有效率为96.77%,高于对照组的74.19%,差异有统计学意义(P<0.05)。观察组的止疱时间、止痛时间及结痂时间均短于对照组,差异有统计学意义(P均<0.05)。结论更昔洛韦联合泛昔洛韦治疗带状疱疹效果显著,止疱时间和结痂时间缩短,有效缓解神经痛,不良反应少,痛苦小,值得临床推广应用。
Objective To observe the clinical efficacy of ganciclovir plus famciclovir in the treatment of shingles. Methods Totally 62 patients were selected as study subjects and randomly divided into observation group and control group with 31 cases in each group. The observation group was treated with ganciclovir injection combined with famciclovir capsule. The control group was treated with famciclovir capsule. Both taking vitamin B1, topical calamine lotion and acyclovir cream. The course of treatment was 7 days. The clinical curative effect, blister time, analgesia time and scab time were observed and compared. Results The total effective rate in observation group was 96.77%, higher than 74.19% in control group, the difference was statistically significant (P <0.05). The blistering time, analgesic time and scab time in the observation group were all shorter than those in the control group, with significant difference (all P <0.05). Conclusion Ganciclovir combined with famciclovir treatment of herpes zoster significant effect, blister time and scab time shortened effectively relieve neuralgia, less adverse reactions, little pain, it is worth promoting the clinical application.