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硝氯酚原为治疗牛、羊等家畜肝片吸虫病的药物。自1974年Rim应用本药治疗朝鲜肺吸虫病的报导之后,国内陆续用此药治疗人体卫氏肺吸虫病和肝吸虫病(华支睾吸虫病)。从这些文献中可以看出,此药对肺吸虫病、肝吸虫病虽然有一定的疗效,但是在安全剂量下也有恶心、出汗过多、肌肉关节疼痛等副作用,并注意到本药对视功能和视器的损伤问题。我们自1979～1983年之间收治3例硝氯酚中毒所致的失明患者现报告如下。
Nitrochlorophenol was originally used to treat cattle, sheep and other livestock fistulas drugs. Since 1974, Rim application of the drug treatment of North Korea Paragonimiasis report, the domestic use of this drug in the treatment of human Paragonimus and paragonimiasis (Clonorchis sinensis). As can be seen from these documents, this medicine has some curative effects on paragonimiasis and paragonimiasis, but also has nausea, sweating and muscle and joint pain side effects at safe dosage, Functional and visual impairment problems. We have reported three cases of blindness caused by ninhydrin poisoning between 1979 and 1983 as follows.