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γ-球蛋白对免疫缺陷患者的感染预防有很大作用,新的静脉制剂问世后其适应症扩展到以免疫学异常为背景的疾患。按每日0.4g/kg 静脉注射5天,特发性血小板减少性紫癜患者的血小板可急剧上升;应用于川崎病患者能使冠状动脉病变的合并频率减少;治疗胰岛素依赖性糖尿病,可使部分病例缓解期延长,胰岛素需要量减少,并对上述治疗的作用机制进行了探讨。本药与激素和免疫抑制剂比较。副作用小,将会有新的适应症。
Gamma-globulin plays a significant role in the prevention of infection in immunocompromised patients. The introduction of new intravenous agents has extended its indications to disorders characterized by immunological abnormalities. Daily intravenous injection of 0.4g / kg for 5 days, idiopathic thrombocytopenic purpura in patients with platelet may rise sharply; used in patients with Kawasaki coronary artery lesions can reduce the frequency of merger; treatment of insulin-dependent diabetes can make some Prolonged remission of cases, insulin requirements decreased, and the mechanism of action of the treatment discussed. The drug and hormones and immunosuppressive agents compared. Small side effects, there will be new indications.