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为了从水环境的角度阐述大骨节病的成因机制,以大骨节病高发的四川省若尔盖县为研究区,系统采集了作为饮用水源的地下水和地表水样38件,测试了其化学成分,发现水中的常规组分和微量组分都偏低,且饮用地表水较地下水更容易患病.通过水化学特征分析,表明水环境中多种组分含量异常是导致病发的重要因素,并从水动力和水化学方面解释了其组分含量异常的原因.采用因子分析的方法,结合当地的区域水文地质条件,进一步揭示了大骨节病发生机制与饮用水中P、F、Se和Mn4种组分的含量密切相关,饮用水中这4种组分含量越低,大骨节病的发病率就越高.
In order to elucidate the causal mechanism of Kashin-Beck disease from the perspective of water environment, 38 samples of groundwater and surface water as sources of drinking water were collected from Zoige County in Sichuan province, which is endemic to Kashin-Beck disease. The chemical composition, It is found that the conventional and trace components in water are low, and drinking surface water is more susceptible than groundwater.According to the chemical characterization of water, it shows that the abnormality of multiple components in water environment is an important factor leading to the disease and From the aspects of hydrodynamics and hydrochemistry, the reasons for the abnormal content of its components were explained.Using the method of factor analysis combined with the local hydrogeological conditions, the mechanism of Kashin-Beck disease was further revealed that P, F, Se and Mn4 Closely related to the content of species composition, the lower the content of these four components in drinking water, the greater the incidence of Kashin-Beck disease.