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目的:统计抽动障碍住院患儿相关实验室检查,分析其对于抽动障碍诊断与鉴别诊断的意义。方法:抽取2013年1月至2014年9月在上海交通大学医学院附属新华医院中医科住院治疗的98例抽动障碍患儿各项主要实验室检查结果进行统计分析。结果:抗“O”异常率为17.35%,与对照组比较P>0.05,铜蓝蛋白均值为0.2719±0.0477,与对照组比较P>0.05,血沉异常率为4.08%,与对照组比较,P>0.05。炎症因子均存在一定异常,异常率最高为IL-2r达14.29%,免疫球蛋白只有Ig M存在1例(1.02%),T细胞亚群各项均存在异常,其中CD4/CD8异常率达25.51%,CD3异常率为12.24%。肝肾功能、血尿常规各项异常率统计基本正常,仅仅少数存在少量异常;结论:抗“O”、血沉和铜蓝蛋白等对TD的诊断和鉴别诊断具有重要意义,同时也应该关注患儿的免疫情况。肝肾功能、血尿常规等项目的监测对选择用药具有指导意义。
OBJECTIVE: To analyze the related laboratory tests of children with tic disorder in hospital and analyze its significance for the diagnosis and differential diagnosis of tic disorder. Methods: From January 2013 to September 2014, we collected 98 cases of tic disorder children hospitalized in Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine and analyzed the main laboratory results. Results: The abnormal rate of anti-O was 17.35%, compared with the control group P> 0.05, the average value of ceruloplasmin was 0.2719 ± 0.0477, compared with the control group P> 0.05, the erythrocyte sedimentation rate was 4.08%, compared with the control group , P> 0.05. IL-2r up to 14.29%, immunoglobulin only IgM in 1 case (1.02%), all abnormal T cell subsets, in which the abnormal rate of CD4 / CD8 was 25.51 %, CD3 abnormal rate was 12.24%. Statistics of abnormal rates of liver and kidney function and hematuria were basically normal, with only a few abnormalities. Conclusion: Anti-O, erythrocyte sedimentation and ceruloplasmin are important for the diagnosis and differential diagnosis of TD, and should be paid attention to Children’s immune situation. Monitoring of liver and kidney function, hematuria routine and other items have guiding significance for the choice of medication.