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一般认为,糖尿病人在妊娠期不用口服降血糖药为好。其理由可能在于:①口服降血糖药在妊娠期效果差;②怕引起新生儿畸彤;③担心增加毒副反应;④担心发生新生儿低血糖。作者认为口服降糖药只要能良好地控制血糖,也可用于妊娠期糖尿病人。据此,对南非的妊娠非胰岛素依赖型糖尿病(NIDDM)患者应用下述方案;首先给予饮食控制,日摄取热卡:肥胖者1000卡,非肥胖者1400~1600卡。若血糖控制不满意,加用口服降糖药:肥胖者用降糖片,非肥胖者则选用优降糖。降糖片最大量可达3g/d,而优降糖最大量可达20mg/d。如单用一种口服药效果不佳则两者合用.若效果仍差,则改用胰岛素.无论
Generally believed that diabetes in pregnancy without oral hypoglycemic agents as well. The reasons may lie in: ① oral hypoglycemic drugs in pregnancy effect is poor; ② fear of neonatal teratogenic; ③ worry about increased side effects; ④ worry about neonatal hypoglycemia. The author believes that oral hypoglycemic agents can be used for gestational diabetes patients as long as they can control blood sugar well. Accordingly, the following scheme is applied to pregnant non-insulin dependent diabetes mellitus (NIDDM) patients in South Africa; First, diet control is given. Daily calorie intake: 1000 calories for obesity and 1400 to 1,600 calories for non-obese people. If not satisfied with the control of blood glucose, plus oral hypoglycemic agents: Obese with hypoglycemic agents, non-obese use of glyburide. The maximum amount of hypoglycemic tablets up to 3g / d, while the maximum amount of glyburide up to 20mg / d. If only one kind of oral medication is not effective, the two combined .If the effect is still poor, then use insulin .No matter