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电刺激下丘脑室旁核观察了14只大鼠盲肠系膜微循环的变化。在0.2～0.6mA的刺激强度下,盲肠系膜各级微动脉及毛细血管括约肌(A_126～66μm、A_218～26μm、A_36.6～18μm)均发生明显的收缩,A_1～A_3管径平均变化分别为9.9±2.8％、19.3±5.6％、46.1±7.1％,在收缩程度上存在A_3>A_2>A_1的现象。并且在A_3微血管的收缩过程中伴有血管运动增强。但微静脉未见收缩反应。刺激后与管径变化相应,微循环血流出现明显减慢,甚至出现停滞或倒流。电刺激后动脉血压平均上升4.9kpa,并呈双相性变化:第一峰波在刺激开始后0.5～2秒出现;第二峰波在刺激停止后6～7秒出现并持续1～5分钟然后缓慢下降。
Electrical stimulation of hypothalamic paraventricular nucleus observed changes in the cecal mesangial microcirculation in 14 rats. Under the stimulation intensity of 0.2 ~ 0.6mA, there were significant contractions of arterioles and capillaries (A_126 ~ 66μm, A_218 ~ 26μm, A_36.6 ~ 18μm) 9.9 ± 2.8%, 19.3 ± 5.6% and 46.1 ± 7.1%, respectively. There was a phenomenon of A 3> A 2> A 1 in the degree of contraction. And A_3 microvascular contraction accompanied by increased blood vessel movement. However, no systolic micro venous response. After stimulation and changes in diameter corresponding microcirculation blood flow significantly slowed down, or even stagnation or back. Arterial blood pressure after electrical stimulation increased 4.9kpa averagely, and showed biphasic changes: the first peak wave appeared 0.5 ~ 2 seconds after the start of stimulation; the second peak wave appeared 6 ~ 7 seconds after stimulation stopped and continued for 1 ~ 5 minutes and then decline slowly.