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目的:对阿奇霉素、头孢唑肟钠、左氧氟沙星、头孢曲松钠治疗下呼吸道感染的药学展开研究。方法:随机纳入2016年3月~2017年3月期间在本院接受诊治的120例下呼吸道感染患者作为观察对象,根据患者入院顺序将其随机分为A、B、C、D四个小组,每组中30例患者,分别给予阿奇霉素、头孢唑肟钠、左氧氟沙星、头孢曲松钠治疗,观察对比四组患者的治疗有效率。结果:A、B、C、D四组的治疗总有效率分别为90.0%、86.7%、86.7%、90.0%,各组间进行比较得出的差异不明显(P>0.05),但C组、D组成本要明显更低,与另外两组进行比较得出的差异具有统计学意义(P<0.05)。结论:阿奇霉素、头孢唑肟钠、左氧氟沙星、头孢曲松钠治疗下呼吸道感染的效果均较好,其中左氧氟沙星成本更低,更加经济划算,值得推广应用。
OBJECTIVE: To study the pharmacology of azithromycin, ceftizoxime, levofloxacin and ceftriaxone in the treatment of lower respiratory tract infection. Methods: A total of 120 patients with lower respiratory tract infection admitted to our hospital from March 2016 to March 2017 were randomly divided into four groups (A, B, C and D) Thirty patients in each group were treated with azithromycin, ceftizoxime, levofloxacin and ceftriaxone sodium respectively. The therapeutic efficiency was compared between the four groups. Results: The total effective rates of A, B, C and D groups were 90.0%, 86.7%, 86.7% and 90.0%, respectively. There was no significant difference between groups (P> 0.05) , The cost of group D was significantly lower, and the difference between the two groups was statistically significant (P <0.05). Conclusion: Azithromycin, ceftizoxime sodium, levofloxacin, ceftriaxone sodium treatment of lower respiratory tract infection are better, including levofloxacin lower cost, more economical, it is worth promoting the application.