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阿维菌素是一种抗寄生虫类抗生素,它主要通过影响虫类的神经系统功能而起到高效的杀灭作用。随着阿维菌素的广泛应用,其引起人体的中毒反应屡见报道。如何安全有效地使用阿维菌素类农药及对其中毒的防治越来越引起人们的关注。目前阿维菌素毒理学的研究主要集中在对昆虫的毒作用,而对哺乳动物的毒作用缺少系统性的研究及描述。现对阿维菌素类化合物的化学性质、哺乳动物毒性作用机制及中毒症状与治疗予以介绍。
Abamectin is an antiparasitic antibiotic that acts as a highly effective killing agent by affecting the nervous system functions of insects. With the wide application of abamectin, the poisoning caused by the human body is frequently reported. How to use abamectin pesticide safely and effectively and how to control its poisoning has drawn more and more attention. At present, the research on avermectin toxicology mainly focuses on the toxic effect on insects, but the systematic study and description on the toxic effect on mammals lacks. Now the chemical properties of avermectins, mammalian toxicological mechanisms and symptoms and treatment of poisoning are described.