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法莫替丁(famotidine)是一种新的组织胺 H_2受体阻滞剂,具有强大的抑制胃酸分泌怍用。据报道其效力为西米替丁的40~100倍,为雷尼替丁的7倍。有报告西米替丁和雷尼替丁均可减少正常人肝血流,本文研究法莫替丁对正常人和慢性肝病患者肝血液动力学的急性作用,并研究了法莫替丁4周和8周给药对慢性肝病合并消化性溃疡的患者的消化性溃疡、肝门静脉血流(PBF)和肝功能的作用。法莫替丁对肝血液动力学急性作用的研究对象为6名健康人,年龄32±5岁,还有8例经活检证实的
Famotidine is a new histamine H 2 receptor blocker with potent inhibitory effects on gastric acid secretion. It is reported that its efficacy for cimetidine 40 to 100 times, for ranitidine 7 times. There are reports of cimetidine and ranitidine can reduce the normal hepatic blood flow, this study of famotidine on normal and chronic liver disease in patients with acute hepatic hemodynamics and the study of famotidine 4 weeks And 8-week administration of peptic ulcer, portal vein blood flow (PBF) and liver function in patients with chronic liver disease complicated by peptic ulcer. Famotidine on acute hemodynamic effects of the study of six healthy subjects, aged 32 ± 5 years old, there are 8 cases confirmed by biopsy