毛发上皮瘤是一种向毛囊分化的良性肿瘤，常与基底细胞癌混淆。应用人类原始抗原（ＣＤ３４）检测７例毛发上皮瘤和１２例基底细胞癌中表达，结果：在正常皮肤血管内皮细胞、血管周围和真皮内梭形细胞、毛囊、小汗腺周围梭形细胞阳性。毛发上皮瘤瘤团周围梭形细胞阳性，而基底细胞癌外周间质阴性，说明ＣＤ３４染色有助于鉴别这两种肿瘤。 Hair epithelial tumors are benign tumors that differentiate into hair follicles and are often confused with basal cell carcinoma. Human primary antigen (CD34) was used to detect expression in 7 cases of hair epithelial tumors and 12 cases of basal cell carcinoma. Results: Fusiform cells were positive in vascular endothelial cells, perivascular, and dermal intrafusiform cells, hair follicles, and hypoechoic glands in normal skin. The fusiform cells around the hair epithelial tumor cluster were positive, while the basal cell carcinoma was negative in peripheral tissues, indicating that CD34 staining helps to identify these two types of tumors.