用放射免疫法测定了81名正常妊娠孕妇羊水中Mb浓度,正常值32ng/ml。对两名已生过一DMD患儿的孕妇作产前诊断。一名在24周时羊水检查表明胎儿男性,Mb浓度29.19ng/ml,在正常范围,产后婴儿脐带血清Mb浓度36.37ng/ml,CPK71.54IU,在正常范围,与产前诊断一致。另一名Mb61.13ng/ml,妊娠18周羊水检查表明胎儿男性,羊水Mb7.15ng/ml,属正常范围,建议继续妊娠。 Radioimmunoassay was used to determine the Mb concentration in amniotic fluid of 81 normal pregnant women with the normal value of 32 ng / ml. Prenatal diagnosis of two pregnant women who have had a DMD. An amniotic fluid test at 24 weeks showed fetal males with a Mb concentration of 29.19 ng / ml. In the normal range, the umbilical cord serum Mb concentration was 36.37 ng / ml and CPK 71.54 IU in the normal range, consistent with the prenatal diagnosis. Another Mb61.13ng / ml, 18 weeks of gestation amniotic fluid examination showed that fetus male, amniotic fluid Mb7.15ng / ml, is a normal range, it is recommended to continue the pregnancy.