This paper presents an integrated relay and its associated protection scheme for power transmission lines. The concept of integrated protection is firstly introduced, in which a centralized protection system or relay provides the protection for multiple power plants or a substation. A novel integrated protection relay based on the combination of a number of protection principles is de- scribed. In the proposed scheme, the specially designed protection relays are installed at each substation of a network and are responsible for the protection of every line section connected to the substation busbar.The combined algorithms with multiple settings are implemented into the relay to cover all the protected line sections.Simulation studies show that the proposed protection scheme is able to produce desirable performance and may offer many advantages over the exist- ing one and great potential for future applications.