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药物疗法近年研究消化性溃疡的药物,仍从制酸和保护粘膜两方面考虑。目前以甲氰咪呱(即西米替丁(Cimetidine)和呋硫硝胺为代表的H_2受体拮抗剂研究较多,是欧美各国这几年治疗十二指肠溃疡最常用的药物。保护粘膜有生胃酮及铋、铝等胶体物质。前者可延长粘液细胞寿命,生成较多粘液以保护胃粘膜;而胶体物质在溃疡表面形成保护性薄膜,属局部疗法,药物吸收甚微。
Drug therapy In recent years, the study of peptic ulcer drugs, still from the acid and mucosal protection considerations. At present, Cimetidine (Cimetidine) and furosemide are the representative H 2 receptor antagonists, which are the most commonly used drugs for the treatment of duodenal ulcer in Europe and the United States in recent years. Mucosa with endogenous ketones and bismuth, aluminum and other colloidal substances.The former can prolong the life of mucus cells to generate more mucus to protect the gastric mucosa; and colloidal substances in the ulcer surface to form a protective film, is a local therapy, drug absorption is minimal.