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本文报告肾病综合征出血热(HFRS)病后残留表现患者的临床-免疫学特点。对象为 HFRS126例,其中男118例,女8例,81%患者年龄16～45岁。按肾功能不全表现程度,重型34例(26.5%),中等型48例(38%),轻型44例(35.1%)。患者分为两组:①组:转归良好组,出院时临床治愈及实验检查结果正常90例(72%);②组:转归不良组,残留表现36例(28%)。残留表现发生率取决于HFRS 严重程度而有所不同:重型41%,中等型21%有残留表现,轻型者最终均完全康复。②组中,58%以上的患者病后1～1.5月,35%患者病后3月,7%患者病后4～6月持续有尿比重低。①组特点是急性发病,短期(3～7天)发热,有些中毒症状、出血及肾病综合征。这些患者经14～20天临床康复。
This article reports on the clinical-immunological characteristics of patients with residual manifestations of hemorrhagic fever with nephrotic syndrome (HFRS). The object of HFRS126 cases, including 118 males and 8 females, 81% of patients aged 16 to 45 years. According to the degree of renal insufficiency, 34 (26.5%) were severe, 48 (38%) were moderate, and 44 (35.1%) were mild. The patients were divided into two groups: ① group: good prognosis group, clinical cure at discharge and the test results were normal in 90 cases (72%); ② group: poor outcome group, residual performance in 36 cases (28%). The incidence of residual manifestations varies depending on the severity of HFRS: 41% in severe form, and 21% in medium form with residual manifestations, with light persons eventually fully recovering. ② In the group, more than 58% of patients were ill from 1 to 1.5 months, 35% of patients were sick after 3 months and 7% of patients continued to have low specific gravity from 4 to 6 months after the illness. ① group is characterized by acute onset, short-term (3 to 7 days) fever, some symptoms of poisoning, bleeding and nephrotic syndrome. These patients after 14 to 20 days of clinical rehabilitation.