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已发现老年人存在脑微出血,被认为是一种小血管疾病(small vessel disease,SVD)的表现。脑和肾小球SVD可能有共同的发病机制,因为这两种器官在解剖学和血流动力学方面存在相似性。该研究旨在阐明高血压患者中肾生物学标志物水平与脑微出血的相关性。方法:磁敏感加权成像用于评估脑微出血是否存在和数量。研究者计算晨尿样本中尿白蛋白/肌酐比值(urinary albumin/creatine ratio,UACR)和血清样本中估算的肾小球滤过率(estimated glomerular fil-
It has been found that cerebral micro-hemorrhage in the elderly is considered as a manifestation of small vessel disease (SVD). The brain and glomerular SVD may share a common pathogenesis because of the anatomic and hemodynamic similarities between the two organs. The aim of the study was to elucidate the association of renal biomarkers with cerebral microbleeds in hypertensive patients. Methods: Magnetic resonance weighted imaging was used to assess the presence and amount of cerebral microbleeds. The researchers calculated urinary albumin / creatine ratio (UACR) in morning urine samples and estimated glomerular fil- leration in serum samples,