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本文报告长期饮用１０％乙醇８ｇ／ｋｇｄ－１的雄性Ｓｐｒａｇｕｅ－Ｄａｗｌｅｙ大鼠睾丸组织过氧化脂质（ＬＰＯ）含量动态变化。饮用乙醇３０天、６０天和９０天的大鼠，睾丸组织ＬＰＯ水平均明显高于同期对照大鼠（Ｐ＜０．０１）；在饮用乙醇６０天之内，ＬＰＯ水平呈上升曲线，６０～９０天期间达平顶；每日饲饮乙醇之前给大鼠护肝宁口服液饮用，则睾丸组织ＬＰＯ水平不升高，且明显低于乙醇组大鼠（Ｐ＜０．０１）。结果表明长期饮酒可以引起睾丸组织过氧化损害，护肝宁口服液能够有效地保护睾丸免遭乙醇的毒害。
This article reports the dynamic changes of testicular lipid peroxide (LPO) content in male Sprague-Dawley rats exposed to 10% ethanol 8 g / kg d-1 for long periods. LPO levels in testis tissue of rats and rats consuming ethanol for 30 days, 60 days and 90 days were significantly higher than that of the control rats (P <0.01). Within 60 days of drinking ethanol, the LPO level showed an ascending curve, The level of LPO in the testis tissue was not increased, and was significantly lower than that in the ethanol group (P <0.01). The results showed that long-term alcohol consumption can cause peroxidation damage in testis tissue, Huganing oral solution can effectively protect the testis from ethanol poisoning.