中性粒细胞胞外诱捕网在血栓性疾病中的作用

来源 :临床血液学杂志(输血与检验) | 被引量 : 0次 | 上传用户:fangfei123456
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中性粒细胞是机体防御病原体入侵的关键细胞,在非特异性免疫应答系统中起着至关重要的作用。中性粒细胞胞外诱捕网(neutrophil extracellular traps,NETs)是新近发现的一种不同于凋亡、坏死以及自噬的死亡方式,通过诱捕作用使机体有效防御病原体感染,是人体重要的先天免疫应答机制。NETs除了参与机体的免疫防御外,还有其不利于机体的一面,NETs被发现大量定位于多种疾病相关血栓,并有刺激血栓形成作用。在我国血栓 Neutrophils are the key cells in defense against pathogen invasion and play a crucial role in the non-specific immune response system. Neutrophil extracellular traps (NETs) is a newly discovered death mode that is different from apoptosis, necrosis and autophagy. It can make the body effectively prevent pathogen infection through trapping, which is an important innate immunity in human body Response mechanism. In addition to participating in the immune defense of the body, NETs also has its unfavorable side to the body. NETs are found to be located in a large number of disease-related thrombosis and stimulate thrombosis. Thrombosis in our country
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