对中成药“骨节灵”中是否非法添加丙酸类解热镇痛化学成分的快速筛查方法进行了研究。以抗风湿类中成药-骨节灵为研究对象,用衰减全反射技术(ATR)采集研究样品的IR光谱,用TQ Analyst 9.0软件中的Discriminant Analysis法,建立了布洛芬(Ibuprofen)、酮洛芬(Ketoprofen)、芬布芬(Fenbufen)等丙酸类解热镇痛药的红外识别模型。用该模型检测了50个供试样品,结果显示:阳性样品和阴性样品的识别正确率为100%,误判率为0。 The Chinese patent medicine “bone joints spirit ” in the illegal addition of propionic acid antipyretic analgesic chemical composition of rapid screening methods were studied. Taking the anti-rheumatic drug, raloxen, as the research object, the IR spectra of the studied samples were collected by attenuated total reflectance (ATR) technique. Ibuprofen and ketorolac were established by Discriminant Analysis in TQ Analyst 9.0 software. Ketoprofen, Fenbufen and other propionic acid antipyretic analgesics infrared recognition model. 50 samples were tested by this model. The results showed that the correct rate of positive samples and negative samples was 100%, and the false positive rate was 0.