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应用脑室微量注射海人酸以选择性破坏小鼠海马ＣＡ３区神经元及苔状纤维集群，结果引起小鼠的记忆保持量迅速下降，半衰期显著缩短，曲线下面积降至对照组的１／４。表明，海马神经元功能状态和突触联结强度的维持，是学习记忆的重要物质基础
Microinjection of kainic acid into the ventricles to selectively destroy the neurons and mossy fiber clusters in hippocampal CA3 region of mice resulted in the rapid decrease of memory retention and the shortened half-life of mice. The area under the curve decreased to 1/4 of the control group . It shows that the maintenance of hippocampal neurons functional status and synaptic junctional strength is an important material basis for learning and memory