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目的比较慢性淋巴细胞性甲状腺炎(CLT)合并良恶性结节的MSCT特征,探讨MSCT的诊断和鉴别诊断价值。方法回顾分析经手术病理证实的74例(79个结节)CLT合并结节的MSCT表现,包括结节的大小、实质部分所占百分比、钙化、边缘、包膜、结节的强化方式及程度,并进行统计学分析。结果有81.82%(18/22)的恶性结节为完全实性,16例(16/57,28.07%)囊性为主的结节全部为良性结节(P均<0.05)。恶性结节钙化多于良性,多为细颗粒钙化,位于病灶内部(P均<0.05)。恶性结节边缘多不清,无包膜或包膜不完整,多均匀强化(P均<0.05)。良恶性结节在结节与结节外甲状腺组织平扫、动脉期及实质期CT值之比差异无统计学意义(P均>0.05)。结论 MSCT有助于鉴别诊断CLT患者合并良恶性结节典型特征。
Objective To compare the features of MSCT with malignant and benign nodules in patients with chronic lymphocytic thyroiditis (CLT) and to evaluate the diagnostic and differential diagnosis of MSCT. Methods The MSCT findings of 74 cases (79 nodules) of CLT combined with nodules confirmed by surgery and pathology were analyzed retrospectively, including the size of the nodules, the percentage of the parenchyma, calcification, margins, enveloping, nodular enhancement and extent , And statistical analysis. Results 81.82% (18/22) malignant nodules were completely solid, and 16 (16/57, 28.07%) cystic nodules were all benign nodules (all P <0.05). Malignant nodules more than benign calcification, mostly calcified, located in the lesion (P all <0.05). Malignant nodules edge more unclear, no capsule or capsule incomplete, more uniform enhancement (P all <0.05). There was no significant difference between benign and malignant nodules in nodules and nodules outside the thyroid tissue, arterial phase and parenchymal CT value (P all> 0.05). Conclusion MSCT can help differentiate typical features of benign and malignant nodules in patients with CLT.