现已清楚地认识到亚硝酸盐和硝酸盐是引起获得性正铁血红蛋白血症的原因,也有关于硝酸甘油引起动物正铁血红蛋白血症的报告。作者报告1例因意外的硝酸甘油过量所致的正铁血红蛋白血症。患者男性,80岁,有心绞痛史,因胸痛、气促入院。入院前两天稍微用力甚至在休息时就有多次胸痛发作,入院前3小时开始持续性胸痛。在入院前36小时内,患者服用0.4mg硝酸甘油片100片,其他药物包括消心痛10mg,每天4次,舌下;2%硝酸甘油软膏5.1cm(2吋)于睡眠时用;心得安40mg,每天4次;速尿40mg/天。患者无发绀史。体检:血压120/70mmHg,脉率70次/分,呼吸28次/分,皮肤轻度发绀,肺底有啰音,颈静脉压 It is now well recognized that nitrite and nitrate are the causes of acquired methemoglobinemia and there is also a report on nitroglycerin caused by animal methemoglobinemia. The authors report 1 case of methemoglobinemia due to an unexpected excess of nitroglycerin. Male patient, 80 years old, history of angina, due to chest pain, shortness of breath hospitalization. Two days before admission a little hard even in the rest there are multiple chest pain episodes, 3 hours before admission began persistent chest pain. Within 36 hours prior to admission, the patient took 100 tablets of 0.4 mg nitroglycerin tablets. Other medications included xiao-hu 10 mg, 4 times a day, sublingually; 2% nitroglycerin ointment 5.1 cm (2 inches) for sleep; , 4 times a day; furosemide 40mg / day. No history of cyanosis in patients. Physical examination: blood pressure 120 / 70mmHg, pulse rate 70 beats / min, breathing 28 beats / min, mild cyanosis of the skin, lung aura, jugular venous pressure