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正常的性分化取决于受精卵的核型,也取决于体内雌雄激素在外周组织引起的生理效应。显然,雌雄激素在某一水平的相对平衡对于性征及性格的维持具有重要意义。就激素作用的各个环节来讲,无论是受体前的,受体水平的,或是受体后的障碍都会影响其在靶细胞的生物效应。男性假两性畸形(male pseudohermaphrodism)是一种男性睾丸部分或全部呈女性分化的遗传性疾患。本病的发病率约占所有新生男婴的1/20,000~64,000。睾丸女性化同时也是原发闭经,不育以及先天性无阴道的常见病因。病人性格特征、青春期的乳
Normal sexual differentiation depends on the karyotype of fertilized eggs, but also on the physiological effects of the androgen in the peripheral tissues. Obviously, the relative balance between estrogen and hormones at a certain level is of great significance for the maintenance of sexual characteristics and personality. In all aspects of the role of hormones, whether it is pre-receptor, receptor level, or the obstacles after the receptor will affect its biological effects in target cells. Male pseudohermaphrodism is a genetic disorder in which part or all of a male testicle is differentiated from female. The incidence of this disease accounts for about 1 / 20,000-64,000 of all newborn babies. Testicular feminization is also a common cause of primary amenorrhea, infertility, and congenital absence of the vagina. Patient personality traits, adolescent milk