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作者报告自1983年元月至1993年12月用酒精保存同种异体骨治疗骨巨细胞瘤60例,主张对肿瘤较小、骨壁完整者采用肿瘤彻底搔刮,75%酒精灭活,异体骨柴植人。对肿瘤较大、骨壁菲薄或不完整者应行大块植人或半关节置换以保留肢体功能。经2年以上随访引例,治愈率达87%。酒精灭活可杀死残存的肿瘤细胞,使细胞表面的蛋白质脱水而凝固。同时彻底刮净异体骨髓,减少术后反应,预防肿瘤复发。它具有制作简单,使用方便等优点。
The authors report the use of alcohol preservation of allogeneic bone for the treatment of 60 cases of giant cell tumor of the bone from January 1983 to December 1993. It is advocated that tumors with smaller tumors and complete bone wall should be completely scraped by the tumor, inactivated by 75% alcohol, and allogeneic. Bone wood planter. For large tumors, thin or incomplete bone wall should be implanted or hemiarthroplasty to preserve limb function. After more than 2 years of follow-up cited, the cure rate reached 87%. Inactivation of alcohol can kill the remaining tumor cells and dehydration and coagulation of the protein on the cell surface. At the same time, the allogeneic bone marrow was thoroughly scraped to reduce postoperative reaction and prevent tumor recurrence. It has the advantages of simple production and easy use.