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目的寻求一种适合本地情况的宫颈病变的筛查方法,探讨高危型HPV检测在宫颈细胞学筛查阴性而疑诊有宫颈病变人群的应用。方法选取2011.3-2013.3年某院筛查的25~65岁的社区妇女192名,宫颈细胞学筛查阴性,而病史体征疑诊有宫颈病变,在其经济条件许可,并与其充分沟通的情况下,进行高危型HPV检测,对高危型阳性者行阴道镜检并在镜下取活检。结果 192名疑诊宫颈病变妇女中,高危型HPV阳性检出率为52.6%,宫颈病变检出率为42.2%,宫颈细胞学筛查阴性而疑诊有宫颈病变且高危型HPV阳性人群中,宫颈病变检出率为80.2%。结论对宫颈细胞学筛查阴性而疑诊有宫颈病变者进行高危型HPV检测,能及早地发现患者,不失为一种经济有效的筛查方法,值得应用于社区和基层医院。
Objective To seek a screening method for cervical lesions suitable for local conditions and to explore the application of high-risk HPV test in cervical cytology negative and suspected cervical lesions. METHODS: A total of 192 community-based women aged 25-65 years were screened in a hospital from 2011.3 to 2013.3 years. Cervical cytology was negative for screening, and cervical lesions were suspected in the history of the disease. Subject to their economic conditions and adequate communication with them , For high-risk HPV testing, high-risk type positive colposcopy and biopsy under the microscope. Results Of the 192 women with suspected cervical lesions, the positive rate of high-risk HPV was 52.6%, the detection rate of cervical lesions was 42.2%, negative cervical cytology screening and cervical lesions were high-risk HPV positive, Cervical lesions detection rate was 80.2%. Conclusions High-risk HPV testing for patients with negative cervical cytology and suspected cervical lesions may be an effective and cost-effective screening method for early detection of patients with cervical lesions, which should be applied in community and primary hospitals.