将雌性小鼠暴露于汞蒸气(0.05mg/m~3,0.20mg/m~3)中,每天2h,每周6d,从同笼前7d至孕15d。观察从出生至90d龄仔鼠生理及行为发育情况,发现在汞接触组与阴性对照组之间游泳发育、听觉警戒、平面翻正、水迷宫及被动回避记忆等有明显差异(P<0.05),汞接触组表现为行为发育迟缓。0.20mg Hg/m~3染毒组还可见仔鼠死亡率增加,学习与记忆力明显下降。 Female mice were exposed to mercury vapor (0.05 mg / m ~ 3, 0.20 mg / m ~ 3) daily for 2 h, 6 days per week from 7 days before cane to 15 days pregnant. The physiological and behavioral development of the offspring from birth to 90 days were observed. There was significant difference in swimming development, auditory alertness, flatness correction, water maze and passive avoidance memory between mercury exposure group and negative control group (P <0.05) , Mercury exposure group showed behavioral retardation. 0.20mg Hg / m ~ 3 also showed increased mortality of pups, learning and memory decreased significantly.