视网膜色素上皮细胞移植治疗相关视网膜疾病的研究正广泛展开 ,由于视网膜色素上皮细胞的同种异体移植产生排斥反应 ,虹膜色素上皮细胞代替视网膜色素上皮细胞移植成为新的研究领域。本文就近年来视网膜色素上皮细胞和虹膜色素上皮细胞形态学和生理功能上的异同进行综述 ,并简述视网膜色素上皮细胞的退行性改变 Retinal pigment epithelial cell transplantation for treatment of retinal diseases is being widely studied, due to allogeneic retinal pigment epithelial allograft rejection, iris pigmented epithelial cells instead of retinal pigment epithelial cell transplantation has become a new field of research. In this paper, the morphological and physiological functions of retinal pigment epithelial cells and iris pigment epithelial cells in recent years are summarized, and the degenerative changes of retinal pigment epithelial cells