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70年代以来,随着对血管生长机理的认识和生物工程新技术的开发与应用,人们发现了一系列与血管生长(angiogenesis)有关的血管生长因子。通过对血管生长和血管生长因子的研究,不但逐步揭示了肿瘤生长血管依赖的机理,为肿瘤的防治提供了新的思路和手段,同时加深了对血管生长调控机制的认识,为一些血管生长相关疾病(如类风湿性关节炎、糖尿病性视网膜病、银屑病等)和血管闭塞性疾病的发病机理和临床治疗的研究提供了新的有效途径。 血管生长素(angiogenin,ANG)是第一个
Since the 1970s, with the understanding of the mechanism of blood vessel growth and the development and application of new bioengineering technologies, a series of angiogenesis-related vascular growth factors have been discovered. Through the study of vascular growth and angiogenic factors, not only the mechanism of vascular dependence of tumor growth has been revealed step by step, which provides new ideas and methods for the prevention and treatment of tumors, at the same time, it deepens the understanding of the mechanism of vascular growth and regulation, New pathways such as rheumatoid arthritis, diabetic retinopathy, psoriasis, and the pathogenesis and clinical treatment of vascular occlusive disease provide new and effective approaches. Angiogenin (ANG) is the first