目的探讨影响非化疗药物致粒细胞缺乏症患者粒细胞恢复时间(间接反映其预后)的临床因素。方法用单变量和多变量 Cox 比例风险模型分析影响52例非化疗药物致粒细胞缺乏症患者粒细胞恢复的预后因素。粒细胞恢复定义为中性粒细胞绝对值>0.5×10~9/L 和>1.5×10~9/L。结果单变量 Cox 风险分析显示感染严重程度、骨髓增 Objective To explore the clinical factors that affect the recovery time of granulocytes (indirectly reflecting its prognosis) in patients with non-chemotherapy drug agranulocytosis. Methods Univariate and multivariate Cox proportional hazards models were used to analyze prognostic factors affecting neutropenia in 52 non-chemotherapy-induced neutropenic patients. Granulocyte recovery was defined as an absolute neutrophil count of> 0.5 × 10 9 / L and> 1.5 × 10 9 / L. Results Univariate Cox risk analysis showed the severity of infection and myelodysplasia