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An efficient synthesis of methyl 4-hydroxy-6-oxo-1,6-dihydro-2-pyridine carboxylates is described.This involves three component reactions between primary alkyl amines,malonyl dichloride and methyl propiolates.
An efficient synthesis of methyl 4-hydroxy-6-oxo-1,6-dihydro-2-pyridine carboxylates is described. This involves three component reactions between primary alkyl amines, malonyl dichloride and methyl propiolates.