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目的了解济源市手足口病病例肠道病毒的感染情况,为制定预防和控制策略提供依据。方法对2012年1—12月济源市临床诊断为手足口病患者的862例标本,运用实时荧光RT-PCR技术检测样本中的肠道病毒核酸。结果济源市2012年862例手足口病病例标本中检出阳性标本742例,阳性率为86.08%;其中肠道病毒71型(EV71)502例,柯萨奇CoxA16 172例,其他肠道病毒68例。结论济源市2012年1—12月EV71是手足口病病例的主要病原体,病例主要为5岁以下散居儿童为主。
Objective To understand the infection of enterovirus in hand, foot and mouth disease cases in Jiyuan City, and to provide the basis for the formulation of prevention and control strategies. Methods 862 cases of hand-foot-mouth disease were diagnosed in Jiyuan City from January to December in 2012. The real-time fluorescent RT-PCR was used to detect the enterovirus nucleic acid in samples. Results A total of 742 positive samples were detected in 862 cases of HFMD in Jiyuan City in 2012, with a positive rate of 86.08%. Among them, 502 cases of enterovirus 71 (EV71), 172 cases of CoxA16 of Coxsackie and 68% of other enteroviruses example. Conclusion From January to December in 2012, EV71 is the major pathogen of hand, foot and mouth disease. The main cases are diaspora below 5 years old.