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目的研究ICU内嗜麦芽窄食单胞菌感染的药敏、临床及细菌学特点。方法回顾性分析ICU内嗜麦芽窄食单胞菌感染患者的临床情况。结果ICU内嗜麦芽窄食单胞菌对大部分抗生素耐药,对亚胺培南100%耐药,对SMZ/TMP、环丙沙星、左氧氟沙星敏感性较高。住院时间长、广谱抗生素长期应用、侵袭性操作是主要的高危因素。结论应用广谱抗生素要慎重,明确的嗜麦芽窄食单胞菌感染可根据药敏选择抗生素,首选药物为喹诺酮类+SMZ/TMP。
Objective To study the drug susceptibility, clinical and bacteriological characteristics of Stenotrophomonas maltophilia in ICU. Methods The clinical data of patients with Stenotrophomonas maltophilia in ICU were retrospectively analyzed. Results The Stenotrophomonas maltophilia in the ICU was resistant to most antibiotics, resistant to imipenem 100%, and sensitive to SMZ / TMP, ciprofloxacin and levofloxacin. Long hospital stay, long-term use of broad-spectrum antibiotics, invasive operations are the main risk factors. Conclusions The broad-spectrum antibiotics should be used with caution. The definite Stenotrophomonas maltophilia infection can be selected according to the drug susceptibility. The drug of choice is quinolones + SMZ / TMP.