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通过测定子宫内膜异位症患者细胞免疫功能以探讨其发病因素。采用单克隆抗体（ＣＤ３、ＣＤ４、ＣＤ８、ＣＤ５６）对２０例子宫内膜异位症患者，２０例子宫肌瘤患者，２０例正常妇女外周血Ｔ淋巴细胞亚群进行检测。结果：与正常妇女比较，内异症组Ｔ３、Ｔ４、Ｔ４／Ｔ８明显下降，有显著差异（Ｐ＜０．０１）；Ｔ８稍高（Ｐ＞０．０５）。与肌瘤组比较，内异症组Ｔ４、Ｔ８稍低，Ｔ３相近，Ｔ４／Ｔ８稍高，无显著差异（Ｐ＞０．０５）。肌瘤组与正常妇女比较，Ｔ３、Ｔ４／Ｔ８明显下降（Ｐ＜０．０１），Ｔ４稍下降（Ｐ＞０．０５），Ｔ８明显上升（Ｐ＜０．０５）。三组间ＮＫ细胞值为肌瘤组＞内异症组＞正常组，无显著差异（Ｐ＞０．０５）。提示：内异症患者细胞免疫功能低下，与子宫肌瘤患者相近。细胞免疫功能失调可能为其发病因素之一。
By measuring the cellular immune function in patients with endometriosis to explore its risk factors. T lymphocyte subsets in 20 patients with endometriosis, 20 patients with uterine fibroids and 20 normal women were detected by monoclonal antibodies (CD3, CD4, CD8, CD56). Results: Compared with normal women, T3, T4 and T4 / T8 in endometriosis group were significantly decreased (P <0.01); T8 was slightly higher (P> 0.05). Compared with myoma group, T4, T8 slightly lower, T3 similar, T4 / T8 slightly higher, no significant difference (P> 0.05). Compared with normal women, myoma group showed a significant decrease of T3, T4 / T8 (P <0.01), a slight decrease of T4 (P> 0.05) and a significant increase of T8 (P <0.05). NK cells among the three groups were fibroid group> endometriosis group> normal group, no significant difference (P> 0.05). Tip: Endometriosis patients with cellular immune dysfunction, similar to patients with uterine fibroids. Cellular immune dysfunction may be one of the pathogenesis.