【摘 要】
：
A highly enantioselective palladium-catalyzed intermolecular tandem Heck/Cacchi reaction of unactivated alkenes with ortho-ethynyl-anilines was developed,which provides a powerful route to access a broad range of enantioenriched 2,3-dihydrobenzofuran-or i
【机 构】
：
Shanghai Key Laboratory of Green Chemistry and Chemical Processes,School of Chemistry and Molecular
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A highly enantioselective palladium-catalyzed intermolecular tandem Heck/Cacchi reaction of unactivated alkenes with ortho-ethynyl-anilines was developed,which provides a powerful route to access a broad range of enantioenriched 2,3-dihydrobenzofuran-or indo-line-substituted indoles bearing all-carbon quaternary stereocenter of interest in pharmaceutical research.Its salient features include inherent atom-and step-economy,high functional group tolerance,mild conditions,broad structural diversity together with excellent enantioselectivities.
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