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目的观察和分析拉贝洛尔联合硫酸镁治疗中重度妊娠高血压综合征的临床效果。方法选取自2014年6月~2015年6月在我院进行治疗的120例中重度妊娠高血压综合征患者作为研究对象,将其随机分成对照组和观察组,医护人员给予对照组的60名患者进行硫酸镁治疗,而观察组的60名患者在对照组基础上给予盐酸拉贝洛尔治疗,对两组患者治疗前后的平均动脉压(MAP)、全天尿蛋白水平、并发症的发生率以及药物是否存在不良反应进行观察,对照这两组患者的临床效果是否存在差异。结果通过治疗,两组患者MAP、全天尿蛋白水平均低于治疗前,观察组明显低于对照组,两个小组之间比较的差异性有统计学意义(P<0.05);观察组并发症发生率为8.33%明显低于对照组的23.33%,两个小组之间比较的差异性有统计学意义(P<0.05);两组患者在治疗期间均未出现严重不良反应。结论通过拉贝洛尔联合硫酸镁的治疗方法,能够有效改善中重度妊娠高血压综合征患者的病症,对提高患者的生存质量具有重要的意义,对腹中胎儿的成长发育未产生影响,值得在临床上进一步推广和采用。
Objective To observe and analyze the clinical effects of labetalol combined with magnesium sulfate in the treatment of moderate-severe pregnancy-induced hypertension syndrome. Methods From June 2014 to June 2015 in our hospital for treatment of 120 cases of moderate and severe pregnancy-induced hypertension syndrome patients were randomly divided into control group and observation group, medical staff to the control group of 60 Patients were treated with magnesium sulfate, while 60 patients in the observation group were given labetalol hydrochloride on the basis of the control group. Mean arterial pressure (MAP), urinary protein level before and after treatment, urinary protein level, complications Incidence and adverse drug reactions were observed, the two groups were compared whether the clinical effect of the difference. Results After treatment, the levels of MAP and urinary protein in both groups were lower than before treatment, the observation group was significantly lower than the control group, the difference between the two groups was statistically significant (P <0.05); observation group complicated The incidence of disease was 8.33%, which was significantly lower than that of the control group (23.33%). The difference between the two groups was statistically significant (P <0.05). No serious adverse reactions occurred in both groups during the treatment. Conclusion The combination of labetalol and magnesium sulfate can effectively improve the symptoms of patients with moderate-severe pregnancy-induced hypertension syndrome, which is of great significance to improve the quality of life of the patients and has no effect on the growth and development of the fetus in the abdomen In the clinical further promotion and adoption.