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本文工作表明:补气药党参水煎醇沉剂对大鼠三种胃溃疡模型(应激型、幽门结扎型、慢性乙酸型)具有预防、保护和促进愈合作用;能明显抑制整体大鼠胃分泌活动及胃运动;对离体豚鼠回肠制备显示拮抗乙酰胆碱的作用;能防止应激所致大鼠胃粘膜内组织胺含量的下降。上述结果说明党参通过影响胃的多种机能产生其抗溃疡效应。
The work of this article shows that the qi-supplemented dangshen decoction and alcohol-depositing agent can prevent, protect and promote healing of three gastric ulcer models (stress, pylorus ligation, and chronic acetic acid) in rats; and can significantly inhibit the whole rat stomach. Secretory activity and gastric motility; showed antagonism to acetylcholine in isolated guinea pig ileum preparation; prevented the reduction of histamine content in the gastric mucosa of rats induced by stress. The above results show that Dangshen produces its anti-ulcer effect by affecting various functions of the stomach.