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人卵黄囊的血管内造血已被细致地观察过。卵黄囊的造血停止,肝成为主要的造血器官。肝造血持续到胎生7个月为止。Fukuda,T.在电镜观察中看到了肝造血中出现未分化的单个核细胞,提出预期的干细胞(presumptive stem cell)一词。近来有人对人胚造血提出卵黄囊、肝及骨等组织的造血三阶段。国内进行了胚肝扩散盒培养细胞的电镜观察,开展了各种因素对造血干细胞的调控研究。迄今为止对造血干细胞的发生学尚乏定
Human yolk sac has been carefully observed intravascular hematopoiesis. The hematopoiesis of the yolk sac stops, and the liver becomes the major hematopoietic organ. Hepatic hematopoiesis lasted 7 months until birth. Fukuda, T. The appearance of undifferentiated mononuclear cells in hepatic hematoplasm was seen in electron microscopy, suggesting the term presumptive stem cell. Recently, some human hematopoietic yolk sac, liver and bone tissue hematopoietic three stages. The electron microscope observation of cultured cells in embryo liver diffusion box was carried out in China and the regulation of hematopoietic stem cells by various factors was carried out. To date, there is still a lack of understanding of the genesis of hematopoietic stem cells