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目的探讨超声刀联合胶原蛋白海绵在巨大甲状腺手术中的应用价值。方法选取2005年1月—2013年9月逸挥基金医院收治的甲状腺疾病患者40例,将患者随机分为对照组与研究组,各20例。对照组患者给予超声刀巨大甲状腺手术治疗,研究组患者在对照组基础上加用胶原蛋白海绵治疗。观察两组患者的手术有效性指标(止血时间、术口愈合时间、术中出血量、术后24h引流量),手术前后负性情绪评分及术后并发症。结果研究组患者止血时间和术口愈合时间短于对照组,术中出血量和术后24h引流量少于对照组,差异均有统计学意义(P<0.05),术前两组患者汉密尔顿焦虑量表(HAMA)和汉密尔顿抑郁量表(HAMD)评分比较,差异无统计学意义(P>0.05),术后研究组患者HAMA和HAMD评分低于对照组,差异有统计学意义(P<0.05),对照组并发症发生率为40%,高于研究组的5%,差异有统计学意义(P<0.05)。结论超声刀联合胶原蛋白海绵在巨大甲状腺手术中具有积极的应用价值,有助于患者康复,改善负性情绪,降低并发症发生率。
Objective To investigate the value of ultrasonic knife combined with collagen sponge in giant thyroid surgery. Methods Forty patients with thyroid disease admitted from January 2005 to September 2013 in Yi Shi Fund Hospital were selected and randomly divided into control group and study group, with 20 cases in each group. Patients in the control group were given giant thyroid surgery with ultrasound knife. Patients in the study group were treated with collagen sponge on the basis of the control group. The operative efficacy indexes (bleeding time, healing time, intraoperative blood loss, postoperative 24h drainage), negative emotion scores before and after surgery and postoperative complications were observed. Results The hemostasis time and the healing time of the patients in the study group were shorter than those in the control group. The amount of bleeding and the amount of drainage after operation were less than those in the control group (P <0.05). The Hamilton anxiety There was no significant difference between HAMA and HAMD scores (P> 0.05). The scores of HAMA and HAMD in postoperative study group were lower than those in control group (P <0.05) ). The complication rate in the control group was 40%, which was higher than that in the study group (5%) (P <0.05). Conclusions Ultrasound knife combined with collagen sponge has a positive value in huge thyroid surgery, which can help patients recover, improve negative emotions and reduce the incidence of complications.