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缺氧缺血性脑病(HIE)是新生儿窒息后的严重并发症。病情重,病死率高,后遗症多。其主要临床表现是惊厥、意识障碍、原始反射及神经肌肉系统的改变等。根据Sarnat氏的临床分期标准,现将我科44例HIE危害较大的Ⅱ、Ⅲ期患儿作一产科因素分析,并结合文献对该症进行讨论。临床资料我科自1981年5月～1986年9月共收治新生儿窒息107例,根据Sarnat氏的HIE临床分期标准,符合Ⅱ,Ⅲ期者44例,其中男29例,女15例(男:女为2:1);早产儿2例,足月儿30例,过期产儿12例;体重:<2500g者7例,～3999g32例,≥4000g 5例;1分钟Apgar评分0～3分者21例(47.7％),4～7分者23例(52.3％);HIEⅡ期25例,Ⅲ期
Hypoxic-ischemic encephalopathy (HIE) is a serious complication after neonatal asphyxia. Severe illness, high mortality, sequelae and more. The main clinical manifestations of convulsions, disturbance of consciousness, the original reflex and neuromuscular system changes. According to the Sarnat’s clinical staging criteria, we now 44 cases of HIE more harmful to stage Ⅱ, Ⅲ children for an obstetric factor analysis, and the literature to discuss the disease. Clinical data of our department from May 1981 to September 1986 were treated neonatal asphyxia 107 cases, according to Sarnat’s HIE clinical staging criteria, in line with stage Ⅱ, Ⅲ 44 cases, including 29 males and 15 females (male : Female 2: 1); 2 preterm children, 30 full-term children, 12 children with obesity; weight: <2500g in 7 cases, ~ 3999g32 cases, ≥4000g in 5 cases; 1 minute Apgar score of 0 to 3 21 cases (47.7%), 4 to 7 points in 23 cases (52.3%); HIE Ⅱ stage 25 cases, stage Ⅲ