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目的 :探究霉变甘蔗是否对小鼠胃粘膜有损伤作用,为霉变甘蔗致病提供实验依据;方法 :随机将小鼠平均分为正常组、低浓度组、中浓度组和高浓度组,每组10只,灌胃20天后处死,立即取胃粘膜做石蜡切片HE染色,镜下观察病变情况;结果 :通过镜下观察,发现实验组均有不同程度的炎症细胞浸润;结论:霉变甘蔗可能会引起胃肠粘膜的炎症反应。
Objective: To investigate whether mildewed sugarcane could damage gastric mucosa in mice and provide experimental basis for the pathogenicity of mildewed sugarcane.Methods: The mice were randomly divided into normal group, low concentration group, medium concentration group and high concentration group, 10 rats in each group were sacrificed 20 days after gavage. Immediately, the gastric mucosa was taken for HE staining and the lesions were observed microscopically. Results: Through the microscopic observation, we found that the experimental group had different degrees of infiltration of inflammatory cells. Conclusion: Sugarcane may cause inflammation of the gastrointestinal mucosa.