喜炎平与利巴韦林治疗小儿手足口病疗效和安全性的评价

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目的:对喜炎平与利巴韦林治疗小儿手足口病疗效和安全性进行分析评价。方法:将手足口病患儿随机分为实验组和对照组,实验组给予喜炎平与利巴韦林联合治疗,而对照组仅给予利巴韦林治疗,观察两组治疗效果及产生的不良反应,作对比分析。结果:疗程结束后,实验组的总有效率为91.34%,不良反应产生率为6.53%;而对照组的总有效率为61.45%,不良反应产生率为22.47%,两组差异具有统计学意义(P<0.05)。结论:喜炎平联合利巴韦林治疗小儿手足口病疗效比单用喜炎平的疗效更为理想,安全性相对较高,适合推广使用。 Objective: To analyze and evaluate the efficacy and safety of Xiyanping and Ribavirin in the treatment of hand-foot-mouth disease in children. Methods: The children with hand-foot-mouth disease were randomly divided into experimental group and control group. The experimental group was treated with Xiyanping and ribavirin, while the control group received ribavirin only. The therapeutic effect and the Adverse reactions, for comparative analysis. Results: After treatment, the total effective rate was 91.34% in the experimental group and 6.53% in the experimental group, while the total effective rate was 61.45% in the control group and 22.47% in the adverse reaction group, with significant difference between the two groups (P <0.05). Conclusion: Xiyanping combined with ribavirin treatment of children with hand, foot and mouth disease than the efficacy of Xiyanping more ideal, relatively high safety, suitable for promotion.
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