用盐皮质类固醇药诱发中度高血压治疗了患血栓闭塞性脉管炎,有足趾局部缺血性溃疡和休息性疼痛的15个病人。在治疗期间,末梢收缩压有明显地增加。14例治疗1—2周后获得休息性疼痛消失,平均8个月后,局部缺血性溃疡就治愈。然后停止治疗。有一例没有获得血压增高,临床效果也不显著,盐皮质类固醇药诱发高压来治疗血栓闭塞性脉管炎的严重局部缺血状态似乎是有价值的。 Moderate hypertension was induced with mineralocorticoid drugs in 15 patients with thromboangiitis obliterans, with toe ischemic ulceration and rest pain. During treatment, peripheral systolic pressure increased significantly. Resting pain disappeared in 14 patients 1-2 weeks after treatment, and after 8 months on average, ischemic ulcers were cured. Then stop treatment. In one case, no increase in blood pressure was obtained and the clinical outcome was not significant. It seems that the salt corticosteroid induced hypertensive treatment of severe ischemic conditions of thromboangiitis obliterans may seem worthwhile.