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目的对血脂肪酶、CRP、IL8在急性胰腺炎诊断及预后判断的价值进行研究。方法将36例急性胰腺炎分为轻重两组,另以20例非胰腺疾病的腹痛患者作为对照组,在入院24～48h测定血脂肪酶、CRP和IL8的血清浓度。结果血脂肪酶在胰腺炎患者中的平均水平为872±91u,明显高于对照组的190±17u,而CRP和IL8在重症急性胰腺炎中的平均水平为161±19mg/L和107.91±15.21pg/ml,明显高于轻症急性胰腺炎的37±7mg/L和32.70±4.07pg/ml。结论血脂肪酶具有诊断急性胰腺炎的价值,而CRP和IL8可以作为判断预后的指标。
Objective To study the value of blood lipase, CRP and IL8 in the diagnosis and prognosis of acute pancreatitis. Methods Thirty-six patients with acute pancreatitis were divided into two groups according to their severity. The other 20 patients with abdominal pain who did not have pancreatic disease were selected as the control group. Serum lipids, CRP and IL8 concentrations were measured 24-48 hours after admission. Results The average level of lipase in pancreatitis was 872 ± 91u, which was significantly higher than 190 ± 17u in control group. The average levels of CRP and IL8 in severe acute pancreatitis were 161 ± 19mg / L and 107.91 ± 15.21 pg / ml, significantly higher than 37 ± 7 mg / L and 32.70 ± 4.07 pg / ml for mild acute pancreatitis. Conclusions Blood lipase has the value of diagnosing acute pancreatitis, while CRP and IL8 can be used as indicators of prognosis.