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目的:总结接受活体亲属肾移植术的患者围手术期肾功能及钾离子浓度的变化,讨论其意义。方法:回顾性分析近期进行的活体亲属肾移植术患者围手术期肾功能及钾离子浓度的变化,记录术后尿量变化并进行分析。结果:共有60名活体亲属肾移植患者纳入研究。手术前患者血肌酐为(827.7±199.4)mmol/L,高于正常值,血清钾离子经术前透析为(5.228±0.847)mmol/L,接近正常范围;术后连续监测显示血肌酐和血清钾离子浓度逐渐下降,于术后4小时开始血肌酐和血清钾离子浓度的变化差异有统计学意义(P<0.01)。结论:活体亲属肾移植术术后早期已经出现肾功能及血电解质明显变化,并逐渐趋于正常值,早期监测肾功能及血电解质浓度,及时处理,围手术期处理十分重要。
OBJECTIVE: To summarize the changes of perioperative renal function and potassium ion concentration in patients receiving living-relative renal transplantation and discuss its significance. Methods: The changes of perioperative renal function and potassium ion concentration in patients undergoing kidney transplant with living relatives were retrospectively analyzed. The postoperative urinary output was recorded and analyzed. Results: A total of 60 living relative renal transplant patients were included in the study. Preoperative serum creatinine was (827.7 ± 199.4) mmol / L, which was higher than the normal value. The preoperative dialysis of serum potassium was (5.228 ± 0.847) mmol / L, close to the normal range; continuous monitoring showed that serum creatinine and serum K (superscript +) concentration gradually decreased. There was a significant difference in serum creatinine and serum potassium concentration at 4 hours after operation (P <0.01). CONCLUSION: Renal function and blood electrolytes have changed significantly in early stage after living-related renal transplantation and gradually become normal values. It is very important to monitor the renal function and blood electrolytes concentration in an early stage for timely treatment and perioperative management.