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动物血入药，历史悠久。早在梁·陶弘景《名医别录》、《本草经集注》中，就有鸡、鸭、豕、狗，鹅等多种动物血的性味，主治功效及口服应用的记载。至明、清时，动物血的功用日益受到临床医学家的重视，据李时珍《本草纲目》及赵学敏《本草纲目拾遗》记载，临床使用动物血已达33种之多。时至近代，动物血的临床应用日趋广泛，不仅应用现代医学对其做了大量深入的研究，而且在剂型方面也进行了重大改革，使动物血的应用手段更趋完善。
Animal blood has a long history. As early as Liang Hongtao’s “Doctors Don’t Record” and “Ben Cao Jingji”, there are many animal blood tastes, indications, and oral applications of chickens, ducks, apes, dogs, and geese. During the Ming and Qing Dynasties, the function of animal blood was increasingly valued by clinical scientists. According to Li Shizhen’s “Compendium of Materia Medica” and Zhao Xuemin’s “Supplement to Compendium of Materia Medica”, there are 33 kinds of clinical animal blood use. From the modern times to the modern times, the clinical application of animal blood has become increasingly widespread. Not only modern medicine has been used to do a lot of in-depth research, but also in terms of dosage forms have also undergone major reforms, so that animal blood application methods become more perfect.