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本文合成了 3-(2’-甲基)丙烯酞氧基-5-甲基异恶唑,给出了优化合成条 件,就3-羟基-5-甲基异恶唑与甲基丙烯酰氯的O-/N-酰化反应的影响因素进行了讨 论,并初步测定了3-(2’-甲基)丙烯酰氧基-5-甲基异恶唑的生物活性。
In this paper, the synthesis of 3- (2’-methyl) propenyloxy-5-methylisoxazole, given the optimum conditions for the synthesis of 3-hydroxy-5-methylisoxazole and methacryloyl chloride The influencing factors of O- / N-acylation were discussed, and the biological activity of 3- (2’-methyl) acryloyloxy-5-methylisoxazole was preliminarily determined.